Solid‐Supported Tetrahydropyran‐Based Hybrid Dipeptide Catalysts for Michael Addition of Aldehydes to Nitrostyrenes

The heterogenization of homogeneous catalysts onto a solid support is step towards more sustainable chemistry. recovery and reuse extremely important from practical, economic environmental point view. In this regards, we report series polymer-supported tetrahydropyran-based hybrid dipeptides that serve as active for the enantioselective Michael addition aldehydes to β-nitrostyrenes. These supported have been designed considering optimal anchor position orientation between catalyst support. Additionally, influence linker length on catalytic efficiency was studied. allowed transformation variety substrates in 76–98% yield with 94–97% enantiomeric excess. Detailed deactivation studies provided information, which allows increase useful life these immobilized catalysts.